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個性化捕獲測序

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個性化捕獲測序

產品簡介:

        基于邁基諾GenCap®捕獲技術專利平臺,臨床科研工作者可以根據自身的研發需求開發訂制不同種類的捕獲試劑和測序服務。相較于普通的高通量測序,捕獲測序有效的降低了測序成本,提高了測序深度,能夠更為精確地發現特定區域序列改變的信息,尤其提高了低頻突變的檢出率。

個性化捕獲訂制流程


產品優勢:

◆ 自主產權捕獲平臺,實現探針訂制、測序、信息分析一站式服務
◆ 捕獲范圍大,可捕獲約200K到50M大小基因組
◆ 適用于多種類型樣品,包括石蠟包埋,適用于不同的測序平臺(Illumina, Ion Torrent,Pyrosequencing)
◆ 人、微生物、動物方向均可開發
◆ DNA和RNA樣本均適用
◆ 可單獨提供捕獲試劑盒及配套試劑服務
◆ 可回郵捕獲好的目標區域片段(50Mb)

 生物信息分析

 
標準化分析 SNP;  InDel;  Somatic Mutation Identification
個性化分析 Copy Number Variation;
Fusion Gene(Fusion Partner, Breakpoint
Identification)
 
序列分析深度:

 對于孟德爾疾病/罕見病:有效序列分析深度>200X;
 對于腫瘤樣本:有效序列分析深度>700-1000X;
 其他物種:普遍>200X,并可靈活定制。


項目周期

 30個工作日捕獲試劑的設計及優化;
 45個工作日序列分析服務及數據分析。


 

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